Pierce Derivatization Gas Chromatography Guide
Derivatization Reactions and Reagents for Gas Chromatography Analysis 85 ii. Analysis of relatively nonvolatile compounds. Reduction of volatility of compounds prior to GC analysis.
Books.google.co.th - Chemical derivatisation of functional groups has proved popular since the beginning of organic mass spectrometry as a means to enhance the stability and volatility of the analytes as well as facilitating structure elucidation. This book provides comprehensive information on the wide range of derivatisation. A Handbook of Derivatives for Mass Spectrometry.
Pierce Derivatization Gas Chromatography Guidelines
Derivatization is primarily performed to modify an analyte's functionality to enable chromatographic separations. For more than 50 years, Regis has been a leader in the manufacture of highly pure derivatization reagents for gas chromatography. The formation of chemical derivatives to facilitate meaningful analysis has long been a common practice in gas chromatography. For the analytical chemist, judicious use of derivatization can be the key to unlocking and simplifying a great many complex and perplexing separation problems.
Derivatization, accomplished through alteration of functional groups, provides:. Increased sample volatility. Improved selectivity and chromatographic efficiency. Enhanced detectability Sample volatility or thermal stability is crucial in GC applications. If a sample does not possess these important characteristics, GC analysis is highly unproductive. Derivatization techniques have been developed to address these issues to ensure successful separations. In GC Derivatization, replacement of active hydrogen in functional groups, such as -COOH, -OH, -NH, and -SH, is the primary area of concern and is accomplished through silylation, acylation, or alkylation.
Download and online. GC Derivatization Reagent Procedures.
The Chromatography Department for more information on how GC Derivatization Reagents can help with your project. Of any reagent.